View Full Version : H1N1 Said To Get Nasty This Fall.
Joe_J.
July 12th, 2009, 02:02 AM
We might do well to keep an eye on this one. An exhaustive amount of information is being compiled here (http://www.timebomb2000.com/vb/showthread.php?t=330395).
Recent case.
The Hamilton County Coroner's office tells Local 12 that samples taken from a 19 year old Dearborn County, Indiana man and sent to the Indiana Department of Health for analysis show the musician died of the H1N1 virus, also known as Swine Flu.
19-year-old Matt Mcintosh, known as "Skinny" died Sunday, July 5 at University Hospital after first feeling ill two weeks ago. His sister Mindy, who is 26, has been at University Hospital with the same symptoms... pneumonia and kidney failure. She is still in critical condition and because of the positive test results from her brother's case, she is now being treated as a probable case of H1N1.
Don Crouse, University Hospital Spokesperson: "Basically, came in with double pneumonia, and renal failure, several days before he had been relatively healthy, performed with a local rock band and had played the Saturday before, so this illness was what appeared to be a fairly quick onset."
Matt is the drummer in the local band "Strange on Display." A neighbor says he became very sick during a performance more than a week ago and called his mother.
Pay Cummins, Neighbor: "She came and got him and when he got home he was coughing, but he was coughing up blood."
The Mcintoshes live in rural Dearborn County, near Moores Hill. Initial calls to Local 12 claimed they got sick after cleaning an outbuilding, a shed or barn and getting into some mold or dust. The hospital is taken a broad treatment approach.
"It's being treated as either viral, bacterial or fungal. We don't really have any clue as to what we're dealing with, yet."
The hospital has sent cultures for tests. A lot of people are anxious for answers.http://www.local12.com/news/local/story/Local-Musician-Died-of-Swine-Flu/N_iYY60Z-0quy8f_8KYuUA.cspx
http://www.cdph.ca.gov/HealthInfo/discond/Pages/SwineInfluenza.aspx
Joe_J.
July 13th, 2009, 11:04 PM
WASHINGTON (Reuters) - The new H1N1 influenza virus bears a disturbing resemblance to the virus strain that caused the 1918 flu pandemic, with a greater ability to infect the lungs than common seasonal flu viruses, researchers reported on Monday.
Tests in several animals confirmed other studies that have shown the new swine flu strain can spread beyond the upper respiratory tract to go deep into the lungs -- making it more likely to cause pneumonia, the international team said.
In addition, they found that people who survived the 1918 pandemic seem to have extra immune protection against the virus, again confirming the work of other researchers.
"When we conducted the experiments in ferrets and monkeys, the seasonal virus did not replicate in the lungs," said Yoshihiro Kawaoka of the University of Wisconsin, who led the study.
The H1N1 virus replicates significantly better in the lungs."
The new swine flu virus has caused the first pandemic of the 21st century, infecting more than a million people, according to estimates, and killing at least 500. The World Health Organization says it is causing mostly moderate disease but Kawaoka said that does not mean it is like seasonal flu.
"There is a misunderstanding about this virus," he said in a statement. "There is clear evidence the virus is different than seasonal influenza."
Writing in the journal Nature, Kawaoka and colleagues noted that the ability to infect the lungs is a characteristic of other pandemic viruses, especially the 1918 virus, which is estimated to have killed between 40 million and 100 million people.
OLD PROTECTION
They tested the virus in blood samples taken from nursing home residents and workers in 1999 in California, Wisconsin, the Netherlands and Japan.
People born before 1920 had a strong antibody response to the new H1N1 virus, meaning their body "remembered" it from infection early in life. This finding supports a study published in Nature in August that also found people who survived the 1918 pandemic still had immune protection against that virus.
Flu viruses change constantly, which is why people can be re-infected and why the vaccine must be changed regularly. Current seasonal strains of H1N1 are distant cousins of both the 1918 pandemic strain and the new H1N1 strain.
"Our findings are a reminder that swine-origin influenza viruses have not yet garnered a place in history, but may still do so, as the pandemic caused by these viruses has the potential to produce a significant impact on human health and the global economy," the researchers wrote.
Other tests showed the virus could be controlled by the antiviral drugs Relenza, made by GlaxoSmithKline, and Tamiflu, made by Roche AG, the researchers said.
The World Health Organization said on Monday that vaccine makers should start making immunizations against H1N1 and that healthcare workers should be first in line to get them.
Companies working on an H1N1 vaccine include Sanofi-Aventis, Novartis AG, Baxter International Inc, GlaxoSmithKline, Solvay and nasal spray maker MedImmune, now part of AstraZeneca.
http://www.reuters.com/article/healthNews/idUSTRE56C3K120090713?feedType=RSS&feedName=healthNews&rpc=22&sp=true
Joe_J.
July 17th, 2009, 09:27 PM
By BETH GADDIS
Published: July 17, 2009
http://www2.tbo.com/content/2009/jul...news-breaking/ (http://www2.tbo.com/content/2009/jul/17/polk-county-man-dies-swine-flu/news-breaking/)
A 31-year-old man died of H1N1 swine flu Thursday evening, the Polk County Health Department confirms.
Polk County has had 72 confirmed cases. Health officials do not believe the cases are related.
"At this point, in terms of a public health concern because of a cluster, which means cases that are related to each other, we have not seen any of that yet," said Dr. Celeste Philip, acting medical director.
This is the second confirmed death in the Tampa Bay area in 24 hours. On Thursday, Sarasota County health officials said a 22-year-old, otherwise-healthy man died from the disease. Doctors are awaiting test results on a 47-year-old man who died at Sarasota Memorial Hospital in the past few days.
Florida has 2,188 confirmed swine flu cases, and health officials say the number will rise.
Doctors urge people to wash their hands thoroughly, stay home from work, school or daycare if they feel sick, and to cover their mouths with a tissue or sleeve if they are coughing.
and
Sarasota man, 47, dies:
FL:
Another swine flu death in Sarasota
Published: Friday, Jul. 17, 2009
http://www.bradenton.com/news/breaki...y/1581697.html (http://www.bradenton.com/news/breaking_news/story/1581697.html)
SARASOTA - A 47-year-man is the second person to die this week from swine flu in Sarasota County.
The county Health Department this morning said it has received notification that the man's death, originally suspected to be caused by swine flu, had been confirmed as caused by the virus.
"These deaths are tragic and a sobering reminder that influenza is serious, and can be fatal. Our staff continues to monitor this disease in our community, and reminds residents to take precautions to avoid the flu,” said William Heymann, medical executive director for the Sarasota County Health Department.
George Witzgall
July 17th, 2009, 11:33 PM
swine flu is a joke, it isn't even real.
OTPTT
July 17th, 2009, 11:35 PM
swine flu is a joke, it isn't even real.
Why are these people dying?
George Witzgall
July 17th, 2009, 11:41 PM
Why are these people dying?
check it out:
swine flu hoax (http://www.google.com/search?hl=en&rls=com.microsoft%3Aen-us%3AIE-SearchBox&rlz=1I7SUNA&q=swine+flu+hoax&aq=f&oq=&aqi=)
Joe_J.
July 18th, 2009, 02:30 PM
Why are these people dying?
They do have swine flu. George is reading too much kwanspiracy stuff. That flu has been around for a long time. In fact, I know a man that got paralyzed from swine flu vaccine many years ago. He had Gilliam Barre syndrome.
A lot of the people dying are from complications and one of the biggest is obesity.
Mike in Denver
July 18th, 2009, 02:48 PM
swine flu is a joke, it isn't even real.
George is right or mostly right on this. Remember, on average about 50 people die in the US every day from flu. Obviously, flu is seasonal, and the 50 figure is an average, but so far, I'm convinced that swine flu is either just an ordinary and extremely mild flu or it is totally invented booga! booga!
From an older post:
"I've spent a couple of days trying to find the average annual flu deaths in the US and Mexico. This information is not easy to dig out. Even for the US the semi-official numbers range from 15,000 to over 30,000. Whatever they are, it's likely that on average 50 or more people in the US die from flu every day."
If, on average, 50 people die in the US from flu each day, I'm betting that thousands die every day in the world from flu. Day in, day out, every day in the world. Even if this "swine flu" is real, it is mild and is spreading no faster than any other flu. I've seen years when every other person I knew had the flu, even some summers. So far, I've not met one person this summer who has had even a cold. What reports there have been from VNN forum members, describe a very mild flu.
Booga! Booga!
Mike
Joe_J.
July 19th, 2009, 12:34 AM
Mike, have a look:
http://www.timebomb2000.com/vb/showthread.php?t=330395
They are tallying up the numbers from all over, including the Kwa. Sort of like what newnation does with nigger crime stories.
Anyway, are you aware that a NIH scientist was digging up bodies of those dead by the Spanish Flu? They were working on breathing life back into it. Not sure what the final results were, but they said the RNA sequence was pretty simple.
Yes, people do die of the flu every year but the oddity with this one is the high numbers of young that die versus the older folk. Besides, the planet is well overdue for some pestilence to bring the pop. numbers down. It happens in nature all the time. I know I have seen it with deer.
Joe_J.
July 24th, 2009, 03:03 PM
http://www.bloomberg.com/apps/news?p...=aljo5vnxK3z8# (http://www.bloomberg.com/apps/news?pid=20601086&sid=aljo5vnxK3z8#)
By Eliana Raszewski and Jason Gale
July 24 (Bloomberg) -- Scientists wondering why swine flu has killed more people in Argentina than almost any other nation are studying whether a more dangerous mutant has emerged.
The Latin American country has reported more than 130 deaths from the pandemic H1N1 flu virus since June. Analyses of specimens taken from two severely ill patients showed subtle genetic differences in the virus, the International Society for Infectious Diseases said in a report via its ProMED-mail program yesterday.
Scientists from Columbia University and Argentina’s National Institute of Infectious Diseases now plan to decode the complete genomic sequences of at least 150 virus samples over the next 10 days to gauge the frequency of the changes and whether they are linked to more severe illness. Major changes in the pandemic virus could erode the effectiveness of vaccines being prepared to fight the scourge.
“We are cautious about the findings until we have more sequences,” said Gustavo Palacios, assistant professor of clinical epidemiology at Columbia University, who is participating in the study. The changes already noted haven’t previously been associated with greater virulence, he said today in a telephone interview from New York.
Roche Holding AG’s 454 Life Sciences unit, which makes genetic-sequencing technology, is helping to decode viruses swabbed from patients’ noses and throats. The sequence data will be shared with other scientists for broader analysis, according to ProMED.
U.S. Fatalities
The pandemic virus has infected at least 125,000 people globally, killing about 800, the World Health Organization said. Only the U.S., with 263 deaths, has recorded more fatalities than Argentina. More than 3,000 people have caught the bug in the country, with the biggest surge in cases occurring in the first two weeks of July.
To cope, hospitals such as the Federico Abete, on the outskirts of the capital, Buenos Aires, converted halls and waiting areas into treatment rooms to double the number of beds to 200. At the peak, 120 swine flu patients were hospitalized at Federico Abete with a death rate of four a day. It now has 90 patients confirmed or suspected to have the virus.
“We could say that we are on a downward trend, but we may have a new outbreak in August, when kids go back to school because this flu isn’t going to disappear,” said Carlos Rubinstein, head of research at the hospital, one of the major pandemic-treatment centers in the province of Buenos Aires. “We see fewer patients sent from other hospitals and fewer people coming in who are concerned they have swine flu.”
Seasonal Strain
Rubinstein said he can’t explain why so many cases in Argentina were fatal. Nine of every 10 cases of flu in the country are caused by the pandemic strain, Health Minister Juan Luis Manzur said on July 6. Rubinstein said it’s possible the virus circulating in Argentina swapped some of its genes with a seasonal strain, spawning a new variant.
Others blame the health system and the distraction of a mid-term election on June 28, which saw the ruling coalition lose majority control of congress and was followed by the resignation of former health minister Graciela Ocana.
“We have a more dramatic situation than in other countries because Argentina delayed taking measures before the mid-term elections,” said health economist Ariel Umpierrez, who heads a nongovernmental organization called Medicos sin Banderas, or Doctors Without Flags, which teaches poor people about hygiene and how to prevent and respond to sickness. “We wasted a lot of time.”
A spokeswoman for the Health Ministry in Buenos Aires didn’t immediately respond to a message left by Bloomberg seeking comment.
The Argentine government ordered companies to give 15 days paid leave to pregnant women and people suffering diabetes and auto-immune diseases. It also closed all public offices -- which led to banks and financial markets not operating -- on Friday, July 10, creating a four-day weekend that started with the July 9 national holiday.
Joe_J.
July 31st, 2009, 07:23 PM
http://www.indystar.com/article/2009...Indiana+family (http://www.indystar.com/article/20090729/NEWS/907290351/1304/LOCAL/Flu+virus+claims+second+member+of+Indiana+family)
Flu virus claims second member of Indiana family
3 weeks after her brother died, woman becomes state's third victim
By Shari Rudavsky and Will Higgins, Indianapolis Star
Posted: July 29, 2009
For nearly a month, Katrina McIntosh shuttled daily from her home in southeastern Indiana to a Cincinnati hospital more than an hour away, where first her teen son and then her adult daughter succumbed to the new influenza virus.
Tuesday afternoon -- the day after Mindy McIntosh died -- McIntosh sat on the porch swing of her Moores Hill home. For the first time since her kids fell ill, she had nothing to do, no place to go.
"I just feel like I should be doing something," she said.
Mindy's brother, Matt, died three weeks ago at 19, the first Indiana resident to die from H1N1 influenza. Mindy, 26, was the third Hoosier to die from the virus, also known as swine flu.
The two fell ill at the end of June a few days after a trip to Kings Island. Katrina and her husband, Mark, will never know where they contracted the virus.
Indiana State Health Commissioner Dr. Judith Monroe refused to comment specifically on the McIntoshes, citing patient confidentiality.
The state confirmed two Dearborn County residents have died of H1N1. The third death was that of a person in Lake County who has not been identified. Monroe said Tuesday that no one should consider themselves immune.
"We know absolutely now that this virus is widely spread, so everyone is at risk of potentially getting this virus," she said.
Statistics suggest that about 40 percent of those who have died from the virus have had underlying pulmonary problems, such as asthma, Monroe said. About 30 percent have had other underlying health conditions.
Since the end of April, there have been 291 confirmed cases in Indiana. Nationally, 43,771 cases and 302 deaths have been attributed to the virus.
The Centers for Disease Control and Prevention estimates that 10 to 20 times more people have had the illness and never been diagnosed, Monroe said.
At this point, H1N1 is the only flu strain circulating in Indiana, Monroe said.
If individuals come in contact with someone known to have H1N1, they should limit exposure to others in the family to avoid contagion for the incubation period, which can last two to seven days, Monroe said.
Those who develop symptoms should self-isolate, sleeping alone and eating in another room, she added.
"There is no question that close household contacts and of course close proximity to anyone is going to increase the risk of spread," she said.
Joe_J.
July 31st, 2009, 07:25 PM
July 29 (Bloomberg) -- Swine flu vaccine makers may rely on a U.S. emergency declaration to use experimental additives made by GlaxoSmithKline Plc and Novartis AG to boost a limited supply of shots that will be available to fight the pandemic.
The ingredients, known as adjuvants, may be added for the first time to flu shots in the U.S. Health officials today are meeting to discuss the additives at the U.S. Centers for Disease Control and Prevention in Atlanta, and to recommend who should receive the limited amount of vaccines drugmakers say they will begin delivering in September or October.
The U.S. Health and Human Services Department declared a public health emergency over swine flu in April, and the Food and Drug Administration has the power to allow the use of unapproved medical products during such a crisis. The U.S. has been slow to approve the use of adjuvants because of safety concerns, and for fear of giving Americans an excuse to avoid getting the shots, said John Treanor, a University of Rochester researcher.
“The question is, do you really feel comfortable throwing this new thing into the mix and do you really need to?” said Treanor, a professor of medicine, microbiology and immunology at the school in Rochester, New York. “I myself, if I had to do it, would really wrestle with that decision.”
http://www.bloomberg.com/apps/news?pid=20601103&sid=a_xObcaSxF2o
Joe_J.
July 31st, 2009, 07:26 PM
HOUSTON, July 30 (Xinhua) -- The A/H1N1 flu death toll in the most populous U.S. State of California has reached 80 with hospitalizations of 699, according to the latest statistics released by the California Department of Public Health (CDPH) late Thursday.
The department said that 28 more deaths have been reported in the past two weeks, a formidable jump from the previous record of 52 released two weeks ago by the federal Centers for Disease Control and Prevention (CDC).
Since the outbreak of the A/H1N1 flu, California has been among the top states leading the nation with most deaths and confirmed cases of the new flu virus. But the department said on Thursday that, beginning from July 16, it has changed the reporting requirements for the A/H1N1 influenza by local health jurisdictions.
The new reporting requirements will track only hospitalized and fatal cases, the department said, adding that non-hospitalized case reporting is no longer needed at this stage of the pandemic.
The department now believes hospitalizations and fatalities provide the most accurate measures of disease severity in California communities and serve the public health goal of tracking A/H1N1 disease trends in the west-coast state.
The A/H1N1 virus is now widespread throughout California and reporting outpatient cases does not assist in further efforts to understand the pandemic, the department said. The state health officials urge people to be well-prepared for the pandemic declared by World Health Organization last month.
http://news.xinhuanet.com/english/20...t_11803786.htm
Joe_J.
August 9th, 2009, 12:14 PM
Mexico is starting to see an increase in swine flu cases in isolated areas. To date, it has confirmed a total of 10,687 cases, including 119 deaths.
With the Southern Hemisphere in the midst of its winter flu season, Chan said officials are keeping a close watch on those countries.
In Washington, the White House said it would hold a high-level meeting next week bringing together top government officials to prepare for the possibility of a more severe outbreak of A(H1N1) influenza.
The meeting was called after the US Centers for Disease Control and Prevention (CDC) estimated that at least one million people in the United States have had swine flu, basing the projection partly on computer models.
Britain, which has officially reported 7,447 swine flu cases, is the hardest-hit nation in Europe. Health minister Andy Burnham said Thursday that Britain will now only give the antiviral to people with the virus after forecasting 100,000 new swine flu cases a day by the end of August.
Australia has the most cases in the Asia-Pacific region, with more than 4,568 confirmed.
http://www.survivetheflu.com/
Joe_J.
August 9th, 2009, 12:19 PM
Camp Devens, Mass. Surgical Ward No 16 29 September 1918 (Base Hospital)
My dear Burt- It is more than likely that you would be interested in the news of this place, for there is a possibility that you will be assigned here for duty, so having a minute between rounds I will try to tell you a little about the situation here as I have seen it in the last week.
As you know I have not seen much Pneumonia in the last few years in Detroit, so when I came here I was somewhat behind in the niceties of the Army way of intricate Diagnosis. Also to make it good, I have had for the last week an exacerbation of my old "Ear Rot" as Artie Ogle calls it, and could not use a Stethoscope at all, but had to get by on my ability to "spot" ' em thru my general knowledge of Pneumonias. I did well enough, and finally found an old Phonendoscope that I pieced together, and from then on was all right. You know the Army regulations require very close locations etc.
Camp Devens is near Boston, and has about 50,000 men, or did have before this epidemic broke loose. It also has the Base Hospital for the Div. of the N. East. This epidemic started about four weeks ago, and has developed so rapidly that the camp is demoralized and all ordinary work is held up till it has passed. All assemblages of soldiers taboo.
These men start with what appears to be an ordinary attack of LaGrippe or Influenza, and when brought to the Hosp. they very rapidly develop the most viscous type of Pneumonia that has ever been seen. Two hours after admission they have the Mahogany spots over the cheek bones, and a few hours later you can begin to see the Cyanosis extending from their ears and spreading all over the face, until it is hard to distinguish the colored men from the white.
It is only a matter of a few hours then until death comes, and it is simply a struggle for air until they suffocate. It is horrible. One can stand it to see one, two or twenty men die, but to see these poor devils dropping like flies sort of gets on your nerves.
We have been averaging about 100 deaths per day, and still keeping it up. There is no doubt in my mind that there is a new mixed infection here, but what I don't know. My total time is taken up hunting Rales, rales dry or moist, sibilant or crepi tant or any other of the hundred things that one may find in the chest, they all mean but one thing here -Pneumonia-and that means in about all cases death.
The normal number of resident Drs. here is about 25 and that has been increased to over 250, all of whom (of course excepting me) have temporary orders-"Return to your proper Station on completion of work". Mine says "Permanent Duty", but I have been in the Army just long enough to learn that it doesn't always mean what it says. So I don't know what will happen to me at the end of this.
We have lost an outrageous number of Nurses and Drs., and the little town of Ayer is a sight. It takes Special trains to carry away the dead. For several days there were no coffins and the bodies piled up something fierce, we used to go down to the morgue (which is just back of my ward) and look at the boys laid out in long rows. It beats any sight they ever had in France after a battle. An extra long barracks has been vacated for the use of the Morgue, and it would make any man sit up and take notice to walk down the long lines of dead soldiers all dressed and laid out in double rows. We have no relief here, you get up in the morning at 5:30 and work steady till about 9.30 P.M., sleep, then go at it again. Some of the men of course have been here all the time, and they are TIRED.
If this letter seems somewhat disconnected overlook it, for I have been called away from it a dozen times the last time just now by the Officer of the Day, who came in to tell me that they have not as yet found at any of the autopsies any case beyond the red hepatitis stage. It kills them before they get that far.
I don't wish you any hard luck Old Man but I do wish you were here for a while at least. It's more comfortable when one has a friend about. The men here are all good fellows, but I get so damned sick o Pneumonia that when I go to eat I want to find some fellow who will not "Talk Shop" but there ain't none nohow. We eat it, live it, sleep it, and dream it, to say nothing of breathing it 16 hours a day. I would be very grateful indeed if you would drop me a line or two once in a while, and I will promise you that if you ever get into a fix like this, I will do the same for you.
Each man here gets a ward with about 150 beds, (Mine has 16 and has an Asst. Chief to boss him, and you can imagine what the paper work alone is - fierce,-- and the Govt. demands all paper work be kept up in good shape. I have only four day nurses and five night nurses (female) a ward-master, and four orderlies. So you can see that we are busy. I write this in piecemeal fashion. It may be a long time before I can get another letter to you, but will try.
This letter will give you an idea of the monthly report, which has to be in Monday. I have mine most ready now. My Boss was in just now and gave me a lot more work to do so I will have to close this.
Good Bye old Pal, "God be with you till we meet again" Keep the Bowels open. (Sgd) Roy.
http://disasterpastor45.blogspot.com/2009/04/camp-devens-mass-surgical-ward-no-16-29.html?zx=67bf88eac4e2a6f4
George Witzgall
August 9th, 2009, 12:23 PM
http://disasterpastor45.blogspot.com/2009/04/camp-devens-mass-surgical-ward-no-16-29.html?zx=67bf88eac4e2a6f4
you are trying to make swine flu into something bigger than it is.
"Keep the Bowels open" wut the fuck?
Joe_J.
August 9th, 2009, 12:34 PM
you are trying to make swine flu into something bigger than it is.
No, it is going to be bigger than what the pinheads think it will be. Read up on the Spanish flu. Keep in mind that a German doc with NIH several years ago dug up the bodies of those that died and was seeking to revive the RNA sequence of that strain.
There have already been mutations in several parts of the world, including the US/Mex border area.
If you were alive in the late 70s, you probably thought that the buttfuck AIDS disease wasn't a big deal, either.
"Keep the Bowels open" wut the fuck?
Had I known you were going to read the thread, I would have clipped that one out. I see it caught your eye.
Joe_J.
August 23rd, 2009, 07:18 PM
Jew camps. The one in the article is the kikey Blue Star camp.
PandemicTamiflu Resistance in North Carolina Summer Campers
Recombinomics Commentary 13:00
August 22, 2009
The nation's first cases of H1N1 resistant to Tamiflu came from a Henderson County camp, health officials said Friday.
Two campers from Camp Blue Star in Henderson County are resistant to Tamiflu, an antiviral drug used to treat the swine flu.
One camper resides in Buncombe County, and the other lives in Florida.
The campers became ill with H1N1 in July while receiving Tamiflu for exposure to other ill campers. Both had mild illness and have since recovered.
"Both are fine," said Tom Bridges, health director for the Henderson County Health Department.
The two cases were discovered by the federal Centers for Disease Control through testing of samples submitted by the Henderson County Health Department through the N.C. State Laboratory of Public Health. Camp Blue Star has completed all summer camp sessions and now is closed for the season.
The above comments describe two more Tamiflu resistant cases in the United States. Like the first two reported cases (http://www.recombinomics.com/News/08170901/H274Y_Fit_US.html), these two cases represent a cluster, strong suggesting the presence of resistant H1N1 as a minor population, which is discovered during or after Tamiflu treatment. Like most of the prior cases these two campers developed resistance while on prophylactic Tamiflu. Although the day of treatment isn't given, the development of resistance in two campers (see map (http://flutracker.rhizalabs.com/flu/gmap0908211757.html?lat=35.509871738383964&lon=-82.8753662109375&zoom=8)) suggests both were infected with H1N1 that contained H274Y
Thus, in one sense these campers are similar to other prophylactic patients, but the clustering is like the immune-suppressed patients in Seattle (http://www.recombinomics.com/News/08150901/H274Y_WA.html), who developed resistance while being treated. The resistance in two patients from the same area raised concerns that the H1N1 was a mixture and resistance was in genetically similar viruses. Those sequences (http://fluboard.rhizalabs.com/forum/viewtopic.php?f=18&t=25&start=8) were released yesterday by the CDC and both sequences gave mixed signals and shared (http://fluboard.rhizalabs.com/forum/viewtopic.php?f=18&t=25&start=10) a polymorphism in addition to H274Y.
The results in North Carolina on samples collected in July raise concerns that these campers seeded additional regions when they left camp. There have been outbreaks in schools in the south (http://www.recombinomics.com/News/08200901/H1N1_South_School.html), in North Carolina and adjacent states (see map (http://flutracker.rhizalabs.com/flu/gmap0908211757.html?lat=34.05265942137599&lon=-82.96875&zoom=6)), and at least one school has recommended prophylactic Relenza for roommates of confirmed college cases, further suggesting that Tamiflu resistance is being detected, but not reported.
Since the campers were infected in July, it is unclear if these cases were among those mentioned by the WHO. Additional cases were acknowledged, but the number and locations were withheld (http://www.recombinomics.com/News/08170902/H274Y_WHO_Locations.html).
These two cases strongly suggest that Tamiflu resistance is widespread and linked to the recent explosion of clusters in schools in the area.
Release of these sequences, as well as more aggressive sequencing of isolates from cases in the area would be useful.
http://www.recombinomics.com/News/08220901/H274Y_NC.html
Dan_O
August 23rd, 2009, 07:49 PM
Read this crazy story about an Israeli biochemist who was going to blow the whistle on the vaccine, but the Secret Service and the FBI got to him first. There was no national coverage of this story either.
http://www.loadedparanormal.com/viewtopic.php?p=7845
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