when I open an exe file I get a message that stats (setup.exe is probably not a 32-bit portable executable try to load it) if you press yes the exe file takes over and nothing is loaded into ollydbg.

My question is:

Is there a way that OllyDbg can Debugg this type of file??

Ollydbg is for 32-bit executables. You're probably trying to debug a 16-bit executable. Try something else like Win32dasm or IDA

Thanks for your reply "1bitshort"
the programe is a 16-bit
and i tried to load it into win32dasm no good
win32dasm opens the file but will not load the programe