Sorry if this is retard level for some of you but i'm new to this line of chemistry.

Does it matter if i use pseudoephedrine hcl or ephedrine hcl?

How can i tell if it's the d or l isomer so that my end product is d (as d is what i want)?

Could someone recommend me a reasonably priced supplier for lab equipment ie a reflux condensor?

PM me if preferred, im based in the uk.

This is for my Aromatherapy conversion/home chemistry course which IS NOT ILLEGAL so please no dick heads telling me off, cheers.

PM me if preferred, im based in the uk.

Even if private messages existed, they aren't private.

Even if private messages existed, they aren't private.

True.

PM me for my email addy. I'd like to discuss techniques with like minded individuals, i have knowledge/experience on other chemistry techniques (synthesis of *legal* hormones).

Im only interested in stuff thats legal. Cheers.

True.

PM me for my email addy. I'd like to discuss techniques with like minded individuals, i have knowledge/experience on other chemistry techniques (synthesis of *legal* hormones).

Im only interested in stuff thats legal. Cheers.
Ok, again, WE DO NOT HAVE A PM SYSTEM HERE. Ya dig? WE DO NOT HAVE A PM SYSTEM.


And the answer to all of your questions is as follows:


Tireless research.

Sorry if this is retard level for some of you but i'm new to this line of chemistry.

Does it matter if i use pseudoephedrine hcl or ephedrine hcl?

How can i tell if it's the d or l isomer so that my end product is d (as d is what i want)?

Could someone recommend me a reasonably priced supplier for lab equipment ie a reflux condensor?

PM me if preferred, im based in the uk.

This is for my Aromatherapy conversion/home chemistry course which IS NOT ILLEGAL so please no dick heads telling me off, cheers.

There's a shit ton of o-chem texts lying around the internet...d/l nomenclature will be in the oldest of textbooks, so you don't need to worry about that. Sounds like a job for:

www.google.com

You can search thalidomide to answer your first question in addition to finding info on your second. As for the third, do some god damn exploring.

Ok, again, WE DO NOT HAVE A PM SYSTEM HERE. Ya dig? WE DO NOT HAVE A PM SYSTEM.


And the answer to all of your questions is as follows:


Tireless research.

Oh yeh no pm lol.... thought i wouldnt get an easy ride but it was worth a try.


look out for a breaking news story coming soon... uk drug monkey dies in home made lab explosion.... i hope u all feel guilty :p

IF anyone does feel particularly charitable then email me chris676693@yahoo.co.uk i have nice info too.

look out for a breaking news story coming soon... uk drug monkey dies in home made lab explosion.... i hope u all feel

Guilty...more like relief:) Helped clean the gene pool of -1 fucktard ;):)

guilty...more like relief:) helped clean the gene pool of -1 fucktard ;):)

lol

:d

You didn't have to edit your original post man. I was leaving this open. It IS (IIRC, it's gone now) a legit thread, and though basic from what I recall, it still fits, and I can't lock it. Well, I can, but you know what I mean. Just because I don't like a topic, doesn't mean I will trash it.


I was just trying to get it through to you that we don't have PMs.


Put your original post back, or something similar so this thread can continue, or I will have to lock it because it has no point as things stand now.

Sorry if this is retard level for some of you but i'm new to this line of chemistry.

Does it matter if i use pseudoephedrine hcl or ephedrine hcl?

How can i tell if it's the d or l isomer so that my end product is d (as d is what i want)?


Ephedrine (http://en.wikipedia.org/wiki/Ephedrine) and pseudophedrine (http://en.wikipedia.org/wiki/Pseudophedrine) have the same chirality at the centre retained in methamphetamine (http://en.wikipedia.org/wiki/Meth).

As the aim in this case would be to remove the hydroxyl group, thus rendering the chirality of that centre in the starting material irrelevant, it doesn't matter whether one were to start with pseudo or ephedrine - assuming the method in question does not alter the stereochemistry at the other chiral centre.

What about having a different salt? (sulphate)

What about having a different salt? (sulphate)
You end up with a base at the end anyway, so the actual salt form is almost a moot point. The only difference it makes is adjusting weight of PSE added, since obviously it is only the PSE base molecule reacting. You pretty much have to account for whatever extra ion is present when calculating your stoich.



Two samples, each weighing the exact same, one is base, and one is a salt, both are ran through, the base will have a higher yield.


If you were to calculate it as the HCl salt weight, and it was actually a base upon reaction, you would end up with unreduced PSE. Ya dig?

You end up with a base at the end anyway, so the actual salt form is almost a moot point. The only difference it makes is adjusting weight of PSE added, since obviously it is only the PSE base molecule reacting. You pretty much have to account for whatever extra ion is present when calculating your stoich.



Two samples, each weighing the exact same, one is base, and one is a salt, both are ran through, the base will have a higher yield.


If you were to calculate it as the HCl salt weight, and it was actually a base upon reaction, you would end up with unreduced PSE. Ya dig?

ah dig ;)

Thanks for that, i read about it over at WD but never bother too look into it:(

Ephedrine (http://en.wikipedia.org/wiki/Ephedrine) and pseudophedrine (http://en.wikipedia.org/wiki/Pseudophedrine) have the same chirality at the centre retained in methamphetamine (http://en.wikipedia.org/wiki/Meth).

As the aim in this case would be to remove the hydroxyl group, thus rendering the chirality of that centre in the starting material irrelevant, it doesn't matter whether one were to start with pseudo or ephedrine - assuming the method in question does not alter the stereochemistry at the other chiral centre.

thx :cool:

Actually, tis true that the 'l Pseudo ((-) Pseudo) won't reduce to meth and retains its effective decongestant properties (whilst having fewer side effects, too, apparently) however, the problem of it not reducing and one not wanting to buy it in error is kind of a moot point.....as Pfizer/Warner-Lambert who hold the patent, I believe, have never sought approval for sale and as such it is NOT available to the public.

So, one cannot 'buy the incorrect' pse as it is an impossibility that one would be served l-pse.

However, ephedrine is different both isomers are available but both reduce to meth BUT one makes classic d-meth and the other l-meth. d-meth is strong and long-lasting whilst l-meth is weaker. There is also, apparently, d/l meth which some say is the better than just pure d-meth due to it's more 'balanced' body and fine nose. A vintage 48 cannot be beaten, apparently.

NB In the UK the sale of ephedrine is illegal and pse has undergone the effects of Paranoid MP's - (dickheads n overweight Booted dykes.....Harriet Harmon (or whatever) - 2nd in line and a total fucking biyatch in the extreme - Extreme Feminist, apparently) and pse has had it's status changed so whereas you could go and buy 3 packs of 24, now you can only buy 12 and they can only be of 60mg (120mgs is available but the pack size will be less as there is a maximum amount of active allowed)


That's it

Actually, tis true that the [l-pseuoephedrine] won't reduce to meth and retains its effective decongestant properties
So, one cannot 'buy the incorrect' pse as it is an impossibility that one would be served l-pse.






Actually, this is not true - All four diastereosisomers will reduce to either d- or l- methamphetamine...

i.e. the optical isomers of pseudoephedrine will reduce to exactly the same compounds as the corresponding isomers of ephedrine.

The point about the lack of availability is valid however, so this becomes a non-issue.