dagnabitt
2008-11-29, 05:45
Ok. Bear with me i'm a little stoned. Hopefully one of you scientitians can entertain one of my potheadisms.
There is some local news about a man who recently donated a portion of his liver to a 6 month old child who needed it. Now, as this child ages this portion of liver will need to grow along with the child. My question is, as this liver grows does it proliferate according to the genetic code (DNA) of the donor or of the recipient?
I suppose this question applies to cellular genesis in general. As cells in the liver die and regenerate, to what extent is the dna of the donor stable? Is there some process by which the recipient dna trans-mutates (???) the donor dna into its own eventually, or does the donated organ retain its genetic integrity throughout aging?
There is some local news about a man who recently donated a portion of his liver to a 6 month old child who needed it. Now, as this child ages this portion of liver will need to grow along with the child. My question is, as this liver grows does it proliferate according to the genetic code (DNA) of the donor or of the recipient?
I suppose this question applies to cellular genesis in general. As cells in the liver die and regenerate, to what extent is the dna of the donor stable? Is there some process by which the recipient dna trans-mutates (???) the donor dna into its own eventually, or does the donated organ retain its genetic integrity throughout aging?